The Author

Joachim Zuther, Lymphedema Specialist. Read more
Lohmann Rauscher
MediUSA

Tactile Medical

Lymphedema and Airline Travel

 

Commercial airline travel is fast, safe and convenient and in the vast majority of cases without any harmful health effects. However, the aircraft environment and other airline-travel related factors may cause certain stresses on the individual affected by lymphedema or the population at risk to develop lymphedema (latent lymphedema). This article is intended to explain the possible deleterious effects that airline travel in pressurized cabins may have on unmanaged lymphedema. The article will also address suggestions to help reduce the risk of triggering lymphedema and prevent existing lymphedema from progressing during and after airline travel.

Lymphedema

The onset of lymphedema is caused by a reduced transport capacity of the lymphatic system resulting in the inability to respond to an increase of lymphatic loads. This causes water and protein to accumulate in the tissues, which could cause chronic alterations and infections if left untreated.

Lymphedema can be defined as high-protein edema and is classified as either primary or secondary; lymphedema may be mild, moderate or severe, affects most often the extremities but may also be present in other parts of the body.

In primary lymphedema the transport capacity is reduced as a result of a developmental abnormality of the lymphatic system. Primary lymphedema may be present at birth, but more often develops later in life with or without obvious cause.

Secondary lymphedema is more common and is caused by surgical interventions involving the lymphatic system. Lymph node dissections, radiation therapy or incisions disrupting the natural pathways of the lymphatic system affects its ability to drain lymphatic loads out of the affected extremity. Secondary lymphedema may arise immediately after surgery or not develop for years.

Chronic venous insufficiencies, infections involving the lymphatic system, trauma, or malignancies affecting the lymphatic system either from the inside or exerting pressure from the outside, may be other causes for the onset of secondary lymphedema.

Lymphedema may be reduced to a normal or near normal size if proper treatment techniques are utilized. However, once lymphedema is present, the lymphatics are never normal again and the affected body part is always at risk of developing more lymphedema.

Effects of Altitude on Air Pressure

cabin pressure1The air’s pressure is caused by the weight of the air pressing down on the earth, the body, and the ocean as well as on the air below. The pressure value depends on the amount of air above the point where the pressure is measured; if altitude increases, the pressure falls. The exact pressure at a particular altitude depends on weather conditions. To understand the general idea of how pressure decreases with altitude the following approximation can be used:
As a rule of thumb, the air pressure drops about 1 inch of mercury for each 1,000-foot increase in altitude or about 0.49 pounds per square inch (psi). At sea level the atmosphere weighs in at about 14.7 psi (101.325 kilopascal or millibar) the pressure of the atmosphere at 8,000 feet is around 10.9 psi (75.156 kilopascal) (1).

Cabin Pressure (Cabin Altitude)

Commercial aircraft are capable of flying at altitudes that are incompatible with human life and yet the passengers and crew are generally not negatively affected because of the on-board environmental and pressurization systems (4). The cabins of aircraft traveling at high elevations are pressurized and the pressure inside the aircraft has to be kept within the design limits of the fuselage. Although pressurized, the cabin pressure is less that that on the ground while traveling at altitude. The cabin pressure of an aircraft intending to cruise at 40,000 feet is designed to rise gradually from the altitude of the airport of origin to around a maximum of 8,000 feet, and to then reduce gently during descent until it matches the air pressure of the destination airport.

cabin pressureRegulations (2) require that commercial aircraft be capable of maintaining a cabin altitude no higher than 8,000 feet at the maximum authorized flight altitude; on most flights the cabin pressure is maintained at around 7,000 feet when cruising at 40,000 feet. In other words, while flying at that altitude the atmosphere within the aircraft is like that on a 7,000 foot mountain peak. Referring to the information above, it is apparent that air pressure (and density) at 7,000 feet are lower than on sea level. Some newer generation airplanes are capable of maintaining a higher cabin pressure.

Cabin Pressure and the Effects on Lymphedema

Many patients report that their extremities had started to swell during air travel. In a 1993 study conducted in Australia 27 of 490 patients reported onset of lymphedema during aircraft flight (15 legs and 12 arms), worsening of existing lymphedema was reported by 67 patients (44 legs and 23 arms) (3).

The most reasonable explanation for this may be inactivity during flight, especially in lower extremity cases.
Most aircraft are crowded, and passengers are frequently uncomfortable and unable to stretch or easily leave their seats. It is a well-known fact that even people with an intact lymphatic system develop swollen feet and ankles during long flights. Inactivity in combination with a compromised lymphatic drainage can have even more serious consequences.

Inactivity, with the legs in a downward position coupled with the subsequent pooling of venous blood will lead to an increase in tissue fluid in the lower extremities. This may be enough to trigger the onset of lymphedema in those patients with latent lymphedema, or worsen already existing lymphedema in the legs.

In addition to inactivity, other factors may play a crucial role in those patients traveling with lymphedema.

The decrease in air pressure (the force exerted on the body by the weight of the air) in the cabin, especially in long-haul flights, in combination with inactivity, may trigger the onset of lymphedema, or exacerbate the symptoms of existing lymphedema.
The reduced pressure does have certain effects on those tissues that are or may be affected by lymphedema (suprafascial tissues). Those effects may allow more fluid to be filtered from the blood capillaries into the tissues. Some of this fluid must be removed by the lymphatic system. An increase in the interstitial fluid content as a result of increased filtration may be just enough to trigger the onset of lymphedema in individuals with compromised lymphatic drainage (latency stages) or increase the swelling in individuals affected by upper and/or lower extremity lymphedema. It can also be assumed (3) that the lower pressure in cabins allows fibrotic capsules in the tissue to become rounded, causing compression and/or distortion of adjacent structures, such as lymphatic collectors and inlet valves of lymph capillaries. This may also result in increased swelling and/or impeded uptake of lymphatic fluid.
In many cases the elastic fibers in the skin are damaged in lymphedema due to the constant stretch caused by the swelling. This may present an additional factor in the worsening of lymphedema under low cabin pressure environment.

Ways to Avoid the Onset of Swelling during Flight

Compression therapy seems to be the most effective measure to counter possible negative effects on lymphedema during air travel. Compression therapy (bandages and/or compression garments) increases the pressure within the tissues. This increase in tissue pressure effectively reduces the accumulation of fluid in the tissues and promotes lymphatic and venous return.
It is highly recommended to perform in-flight exercises. Airlines generally provide a pamphlet or video presentation on in-flight exercises, which are especially beneficial if they are performed while wearing compression bandage or garment.

Useful Tips for the Airline Traveler

Plan ahead:

1. Seek the advice of your physician and your lymphedema therapist if there are any questions.
2. Carry your medication with you. If your destination is located in hot or mosquito-infested areas take precaution (sun screen, insect repellants, and antibiotics).
3. Bring your skin lotion; the air in pressurized cabins is extremely dry.
4. If possible request an exit seat, which gives you more legroom. Definitely request an aisle seat so you can get up periodically without disturbing the person sitting next to you.
5. Allow ample time to check in and reach your departure gate.
6. Wear loose, comfortable clothing and comfortable shoes that have been worn previously. If you have lymphedema of the leg do not take off your shoes during the flight.
7. Make sure that you can manage your luggage. If you travel with another person or a group ask someone else to carry the luggage for you. Should you travel on your own, take a smaller suitcase (preferably one with wheels). Don’t lift your luggage from the baggage carousel with your swollen arm.
8. Check the quality of your compression garment. If you have more than one garment, take the extra one with you as a back up. Remember, if your destination is located at high altitudes you need to take the same precautions as for your flight. Take extra bandages (short-stretch) with you.

Inflight:

1. Relax and enjoy your flight.
2. Eat lightly.
3. Drink plenty of water or fruit juices.
4. Do not place anything under the seat in front of you so you can stretch and exercise your legs.
5. Stand up and walk around the cabin periodically – make sure to observe the fasten seat belt light.
6. Ask somebody else to place your carry-on luggage in the overhead compartment.
7. Make sure to perform some easy to remember “muscle pump” exercises (roll your feet; lift the heels and toes alternating, etc.). Ask your therapist about recommended exercises during the flight.
8. Elevate your arms as often as possible if you have upper extremity lymphedema.
9. Wear your compression garments!
• If you have a stocking with an open toe you may apply bandages on your toes and any other part of your foot that may be exposed.
• It is necessary to wear a glove in addition to your arm sleeve. If you have a gauntlet without finger stubs, you should bandage your fingers.
• It is also a good idea to wear an additional short-stretch bandage on top of your garment to counter the effects of low cabin pressure – talk to your therapist!

Arrival:

1. Do not remove your garment and any additional bandage materials before you reach your final destination.
2. Upon arrival at your hotel, etc. a rest should be your top priority. Make sure to have your limb elevated. A few more exercises with your garments in place would be beneficial.
In addition to the information above, please keep in mind weather you are at home or on vacation all the usual precautions your therapist taught you still apply (you may also visit the National Lymphedema Networks website at www.lymphnet.org to read up on the “Risk Reduction Practices” for upper and lower extremity lymphedema).

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Literature:

1: Linda D. Pendleton: Staying Alive; AOPA Pilot Oct. 2002, Vol. 45 No. 10 pages 121-122
2: Electronic Code of Federal Regulations 14 CFR, Chapter 1, Part 25, Section 25-831
3: JR & J Casley-Smith: Lymphedema Initiated by Aircraft Flight; The Journal of Aviation, Space and
Environmental Medicine. Vol 67, No 1; Jan 1996
4: Niren L. Nagda and Michael D. Koontz: Review of Studies on Flight Attendant Health and
Comfort in Airliner Cabins; The Journal of Aviation, Space and Environmental Medicine 2003;74:101-9

23 comments to Lymphedema and Airline Travel

  • Judith Nudelman

    Joe, this is invaluable. After the NLN backed off recommending people with risk of lymphedema fly with compression–based on 2 very flawed studies–it’s left people at risk in a quandary and with the belief that compression on air flights is harmful. This great post allows people and providers to make a truly informed decision. Also, thank you for reiterating the need to compress the hand when you compress the arm. Far to many patients are told to “wear a sleeve”. Amazing post, and you provide a tremendous benefit to the community of lymphedema patients and providers.

  • Regina Schur

    I am Regina’s husband Mort. We are both in our 90’s and travel does not appear possible unless there is a resolution on either coast. We live in our home in Northbrook, Ill. Her lymphedema is compounded by absence of cartilage in both knees. (bone on bone) which is causing severe pain in walking and needs to be treated through nerve ablation or ???.

    Thank you for formulating the article….and please put us on your communication list.

  • Thank you, Joe, for this guidance. I have some other hints to share based on clinical knowledge of the pathology of lymphedema, since there are so few randomized controlled trials published.
    1. If you wear a circular knit elastic sleeve it is important to exercise your muscle pump of the arm to keep the lymph moving. Elastic sleeves are not recommended for sleeping since, in the absence of movement. The resting pressure of an elastic sleeve could retard, not promote, lymphatic draining. I recommend a non-elastic sleeve for flying, such as a Tribute, JoviPak, CircAid, FarrowWrap, etc. And always pack a foam “stress ball” that you can squeeze while sitting in your seat.
    2. Your recommendations for foot movements for lower limb lymphedema are excellent. There are some commercial devices available that make this easier. Some look like rockers, some like pedals, and they fold up real small for traveling.
    3. If you normally self bandage, this is probably the best way to travel. In the early days of TSA inspections you had to go thru a special cast X-Ray, but I believe tha the newer inspection machines can handle a bandaged limb. Something to look into.

  • Pamela Hain

    I just returned from flight to and from Glasboro Scotland. After about 4 hours in the air, I was able to stand up and use the restroom when the other passengers next to me got up. When I stood in the aisle my left leg had absolutely no muscle strength and I fell forward like a tree being felled. The airline attendants were all over me the rest of the trip, they had to fill out a statement of what happened, and they had a wheel chair for me when I arrived.
    I was wearing compression garments on legs. Is this a usual occurrence?

    • Joachim Zuther

      No, this is certainly not something you would consider a usual occurrence and I doubt it had anything to do with your compression garments

  • Katrina

    Thank you so much for this detailed info! I’m at risk of lymphedema and debating whether to fly for first time next week. I have a compression sleeve ready to use. Do you happen to have any info on how long after lumpectomy/surgery (4 lymph nodes removed), and radiation it is best to wait before flying? I had surgery last April, and ended radiation late July. Also curious: if I’m taking flight with stop over, is it better to have long stop over (e.g. several hours before 2nd leg of journey) so as to allow for longer higher pressure time? Or is it better to have quick turnaround (e.g. 45 mins. btw. flights) so as not to “confuse” the arm with, for example: 5 hours in air, 5 hours on land (take off sleeve after an hour or 2?), and then 5 hours in air again? I could also do 3 legs of journey if that is better. Thanks for any insights!!!

    • Joachim Zuther

      As long as you use your compression sleeve you should not have any issues – the length of a stop-over is not relevant.

  • Debbie

    I have lymphedema of upper extremities. I currently wear compression garments (sleeves and gloves with finger tips cut out) during the day and remove them at night. I am also wearing a compression bra 24 hours a day utilizing the swell spots inside the bra. I was planning a trip to Uganda to see family when all of this occurred. It is a 22-24 hour flight. I have such mixed emotions in planning a trip like this for several reasons. I know I would be flying for an extensive period of time and I would be going to a third world country with the risk of insect bites and contaminants. I realize the effects could be detrimental and at the same time I battle the desire to see loved ones. I don’t want to make the wrong/poor choice. May I ask what your advise would be to someone like me? Thank you for any help/guidance that you could give!

    • Joachim Zuther

      Dear Debbie: Obviously you are aware of the risks associated with a long airplane trip and traveling to an area where insect bites and secondary infections may be an issue. So the decision is certainly up to you. As long as you know how to take care of your extremity and carry first aid materials, such as an alcohol swab, band-aid and anti-inflammatory medication in case of an infection, you should be well prepared in case you decide to go.

  • Pam

    I went on a long flight 18hr (2 stops)(plane changes) wearring 30-40mmg compression hose. Absolutely no problems upon arrival amd during trip. On flight back home, slept durimg most of flight and did not walk n plane. Once home, no problems for ine month and them experienced alot of pain in my knee area and behind knee. I am wondering is this couldd be the result of the long flight? Legs have some pain, esp upon standing. it walks out….

    I want to go on another ling flight and wonder ….

  • Tracey

    HEAD AND NECK LYMPHEDEMA:
    WHat is the protocol for someone that has head and neck lymphedema during air travel?
    Do they perform exercises or should they wear compression?
    I have tried searching this question and can’t seem to find information on it.
    HELP!!

    • Joachim Zuther

      During daytime hours the effects of gravity assist in limiting the accumulation of fluid in the head and neck area. Compression is more important at night in these cases. I would recommend exercises during airline flight.

  • So greatful for this site!!! This is my only true source of knowledge. I have trancal lymphedema , left side, experiencing headaches as well, and some strange pain (mild) behind left ear down to the neck; is it associated with lymphedema? Had mastectomy, implant and radiation on left breasr. Need another surgery for adjustments, is it safe to have a surgery? Thank you

    • Joachim Zuther

      Luba: It is unlikely that the pain symptoms you are experiencing are associated with trunkal swelling. As long as you know how to effectively manage your lymphedema, you should do well.

  • Sung Joong,kim

    Hi! Joe. How are you? Do you remember me. I’m first Korean student. Keep in touch with me.

  • Sue Taylor

    I have lymphedema in right arm due to all nodes being removed due to breast cancer in 2008. I also have lipedema in both legs and both arms. Before my lipedema was diagnosed, my therapist said, for air travel, to be sure to remove my custom compression sleeve and put on my Reed sleeve for the duration of my flight. I have done this consistantly. However, I have never seen another passenger wearing a Reed sleeve, and on every flight, the flight attendants ask about it… and say they have never seen others do this. Am I the only one being compliant, or was this recommendation not accurate? Also, some lipedema patients are wearing 2 layers of 15/21 mmHg graduated compression micromassage sleeves (non-custom) while flying. Is this a good plan? (If these particular women have lymphedema, it is probably mild.)

    • Joachim Zuther

      Dear Sue: The advice given to you by your therapist was certainly appropriate. Due to the lower cabin pressure it is important to wear sufficient compression in order to avoid increase in swelling.

  • Ann

    Hi Joachim. Thank you for all the incredible information on your site, it has helped me so much. But one thing I can’t find is any information relating to Endermologie. I have heard of two machines by LPG, the Cellu M6 used in medical/semi-medical treatments, and the WellBox, a home version. I have also read research articles showing its results as being as effective as MLD for lymphoedema(both carried out by trained and qualified physios)and on its use in lipoedema both before liposuction surgery (particularly in Europe), and independent of it for reduction of fibrosis in lipoedema. I have not yet found any negative research. I have extensive lymphoedema in arms/trunk/legs, secondary to autoimmune connective tissue disease, and lipoedema in my legs and arms. Do you have any information on the suitability of endermologie when both conditions are present? If it is suitable, do you think the home version is worthwhile (the cost to buy the home machine is the same as the cost 1 set of 15 treatments from a professional using the medical grade machine). I have MLD once a month, do self massage daily, exercise daily, good diet, and wear wrap compression at night and elastic compression by day. My treatment plan works well and has reduced my lymphoedema by 30kg, so this would be in addition, not replacing anything. Thanks for your help.

    • Joachim Zuther

      Ann – there is absolutely no proof, or any study that Endermologie, also known as Lipo-Massage, has any positive effect of lymphedema and/or lipedema.

      • Ann

        Thank you Joachim – I was concerned that all the studies I found may have been ‘sponsored’ by the developer, as they all seemed too good to be true. I appreciate you providing unbiased expert advice.